Management Strategies for Liver Fibrosis
نویسندگان
چکیده
منابع مشابه
Management strategies for liver fibrosis.
Liver fibrosis resulting from chronic liver injury are major causes of morbidity and mortality worldwide. Among causes of hepatic fibrosis, viral infection is most common (hepatitis B and C). In addition, obesity rates worldwide have accelerated the risk of liver injury due to nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Also liver fibrosis is associated wit...
متن کاملCurrent strategies for quantitating fibrosis in liver biopsy.
OBJECTIVE The present mini-review updated the progress in methodologies based on using liver biopsy. DATA SOURCES Articles for study of liver fibrosis, liver biopsy or fibrosis assessment published on high impact peer review journals from 1980 to 2014. STUDY SELECTION Key articles were selected mainly according to their levels of relevance to this topic and citations. RESULTS With the rec...
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Transient elastography and the acoustic radiation force impulse techniques may play a pivotal role in the study of liver fibrosis. Some studies have shown that elastography can detect both the progression and regression of fibrosis. Similarly, research results have been analysed and direct and indirect serum markers of hepatic fibrosis have shown high diagnostic accuracy for advanced fibrosis/c...
متن کاملAnimal Models Of Liver Cirrhosis And Fibrosis
Animal modeling is a crucial necessity in clinical studies of liver diseases. Authenticity of the data which are produced using this tool under different conditions and accuracy of the analyses and assessments which would be based on such data sets is completely dependent on the adoption of a standardized methodology for analyzes and assessment of these data sets. Cirrhosis and Fibrosis are amo...
متن کاملEvolving therapies for liver fibrosis.
Fibrosis is an intrinsic response to chronic injury, maintaining organ integrity when extensive necrosis or apoptosis occurs. With protracted damage, fibrosis can progress toward excessive scarring and organ failure, as in liver cirrhosis. To date, antifibrotic treatment of fibrosis represents an unconquered area for drug development, with enormous potential but also high risks. Preclinical res...
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ژورنال
عنوان ژورنال: Annals of Hepatology
سال: 2017
ISSN: 1665-2681
DOI: 10.5604/16652681.1226814